For players ages 4 - 16, District 53 offers Little League Baseball and Girl's Fast-Pitch Softball including an Intermediate (50/70) program, a Junior and Senior League program for both sports.

District 53 was formed in 1966 and reconfigured in 1973, again in 2007 and lastly in 2016. It is the proud home of 14 Leagues from Solano, and Napa counties. These leagues include: American Canyon, Benicia, Calistoga, Cordelia Tri-Valley, Fairfield Atlantic, Fairfield Pacific, Napa American, Napa National, St. Helena, Sonoma, Suisun American, Vallejo American, Vallejo National and Yountville.

District 53 has a meeting of all leagues each month. The meetings are normally held the fourth Thursday of each month and cover a wide range of topics including New President Orientation, Player Agent Training, Scorekeeping Basics, Umpire Basics and Post-Season Information. The meeting is hosted by a different league each month with the host league providing dinner at 6:30 prior to the meeting start time of 7:00. Notes and agendas are posted on the District 53 website.